Effect of Difference in Production Methods of Composite Wound Dressings Produced from Bio-nanofibers by Electro-spinning Technique on Their Functional Properties

Authors

1 Professor of Textile Metrology Chemical Metrology Division National Institute of Standards

2 Professor And Head of The Department of Spinning, Weaving And Knitting, Faculty of Applied Arts Damietta University

3 Assistant Lecture At Department Of Spinning Weaving And Knitting, Faculty of Applied Arts Damietta University

4 Lecture At Department of Spinning, weaving and Knitting department, Faculty of Applied Arts Damietta University

Abstract

Nowadays, modern wound dressings appear to facilitate wound healing by altering the wound environment and interacting with its surface to optimize the healing process. Electro-spinning is considered the simplest technique being used to produce nano-fibers. The electro-spun nano-fibers have amazing properties that make them perfect for use in wound dressing. Biopolymers are considered very useful for wound dressings due to their properties such as compatibility, biodegradability, and non-toxicity. In this research, a composite wound dressing was made, consisting of two layers. The first layer consisted of electro-spun bio-nano-fibers, and the second layer was fabrics difference in production methods. Where the research aims to study effect of difference in production methods of fabrics on the functional properties of those dressings. Four types of biopolymers (chitosan, cellulose acetate, gelatin, and poly-vinyl alcohol) were used to prepare three different composites and using them for the electro-spinning process. Three types of fabrics (woven, nonwoven, and knitted) are used to receive the bio-nano-fibers on their surface. The bio-nano-fibers were characterized by SEM, and the final wound dressing's functional properties were evaluated through thickness, air permeability, wettability, and antimicrobial tests. It was noticed that the basic fabric of wound dressing's production method influenced some of its functional properties. Wound dressings made of knitted fabrics achieved the highest results in thickness and antibacterial against E. coli, while those made of woven fabrics achieved the highest results in air permeability and antibacterial against S. aures. While the type of fabric did not affect the wettability and antifungal properties.

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Main Subjects


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